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Blackcurrants may help asthmatic patients | Natural chemicals from blackcurrants may help breathing in some types of asthma, claims a preliminary study. The study by New Zealand company Plant & Food Research found a compound from a New Zealand
blackcurrant may reduce lung inflammation with a multi-action assault in allergy-induced
asthma. The compound was found in laboratory experiments to enhance the natural
defence mechanisms in lung tissue by both suppressing inflammation-causing reactions
and minimising inflammation. The findings are published in the journal Molecular
Nutrition and Food Research. Fruit consumption has been shown to reduce symptoms
in allergy-induced asthma yet this research is the first to give insights into
the mechanism by which this may occur. The researchers identified that the component,
epigallocatechin, reduced inflammation in lung tissue. Epigallocatechin is a known
antioxidant and a major component of proanthocyanidins found in blackcurrants.
In the Plant & Food Research study, led by Dr Roger Hurst, cells from lung tissue
were used to test the effects on the immune system of a proanthocyanidin rich
extract, from blackcurrant cultivars grown in New Zealand. When the lungs are
exposed to allergens, the body's natural response is to attack the perceived foreign
body which in some individuals results in long-term inflammation. Selective compounds
found in fruit and vegetables may work together with the body's own natural defence
mechanism to suppress long-term lung inflammation. This study shows that epigallocatechin,
from blackcurrants, works in conjunction with other natural immune responses that
occur at the same time to reduce inflammation. These actions are distinct from
the inflammation-reducing activity of another group of compounds, anthocycanins,
which are also rich in blackcurrants. Anthocyanins are known for their antioxidant
properties and, interestingly, have been shown by Dr Hurst's research group to
also influence inflammatory mechanisms and complement the body's own natural immune
responses. The research shows some compounds in fruit thought to promote health
with their antioxidant activity are keeping us well by other means. "To find natural
compounds that potentially reduce lung inflammation and complement the body's
own immune response is an exciting breakthrough," says Dr Hurst. "Should we discover
more about how this works we may eventually develop foods containing these compounds
that could provide more natural alternatives to assist conventional drug treatments
for asthma and even other allergic re-actions."
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