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Oz scientists in TB drug breakthrough | Scientists in Australia have said that they have made a new discovery that could lead to the first novel drug for Tuberculosis (TB) in almost fifty years. Dr Nick West, Associate Faculty of the Mycobacterial
group at Sydney 's Centenary Institute, is looking at the genetics of TB in the
hope they will reveal a way to reduce the impact of one of the deadliest diseases
in the world. "When someone is infected with TB they either become sick immediately
or the disease stays inactive, latent," West said. "Unfortunately, the antibiotics
we use to fight TB aren't effective against latent TB and can only be used when
the disease becomes active. This is a major problem as 1 out of 10 people who
have latent TB will develop the active disease, becoming sick and contagious,"
West added. West and his team have made a vital discovery in the development of
a new drug that could cure TB in the latent stage. If the project succeeds, it
will be the first new treatment for TB since 1962. "We have investigated a protein
that is essential for TB to survive and we have had some success in developing
a drug that will inhibit this protein. Our goal over the coming months is to find
out the full extent of this drug's potential," West said. "If we can figure out
a way to treat TB when it's in a latent stage, then we could save millions of
lives throughout the world," West added.
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