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Walnuts may help fight prostrate cancer | Walnut consumption may help slow the growth of prostate cancer in mice, a new study has found. What's
more, the nut has beneficial effects on multiple genes related to the control
of tumor growth and metabolism, UC Davis and the U.S. Department of Agriculture
Western Regional Research Center in Albany , Calif. have found. The study, by
Paul Davis, nutritionist in the Department of Nutrition and a researcher with
the UC Davis Cancer Center, announced the findings at the annual national meeting
of the American Chemical Society in San Francisco . Davis said the research findings
provide additional evidence that walnuts, although high in fat, are healthful.
"This study shows that when mice with prostate tumors consume an amount of walnuts
that could easily be eaten by a man, tumor growth is controlled," he said. "This
leaves me very hopeful that it could be beneficial in patients." Many clinical
studies have demonstrated that eating walnuts -- rich in omega-3 polyunsaturated
fats, antioxidants and other plant chemicals -- decreases the risk of cardiovascular
disease. In the latest study, Davis fed a diet with whole walnuts to mice that
had been genetically programmed to get prostate cancer. After 18 weeks, they found
that consuming the human equivalent of 2.4 ounces of walnuts per day resulted
in significantly smaller, slower-growing prostate tumors compared to mice consuming
the same diet with an equal amount of fat, but not from walnuts. They also found
that not only was prostate cancer growth reduced by 30 to 40 percent, but that
the mice had lower blood levels of a particular protein, insulin-like growth factor
(IGF-1), which has been strongly associated with prostate cancer. Additionally,
Davis and his research colleagues looked at the effect of walnuts on gene activity
in the prostate tumors using whole mouse gene chip technology, and found beneficial
effects on multiple genes related to controlling tumor growth and metabolism.
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