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Holy Grail of medicine - boon to humanity or cannibalisation? | Dr Randolph Corteling and senior scientist Julie Heward are part of a team in UK that is testing foetal stem cell therapy to cure the killer diseases of old age - a covert operation that could save millions of lives or could be labelled as 'cannibalisation of children'. But there is another reason for the secrecy - these cells have potentially
huge commercial value if human clinical trials succeed. The new trial aims at
pioneering a technique that could see stem cells available to the mass market,
off-the-shelf. And it would not prevent disease, it would be a cure. The treatment
will involve a hole of about a quarter- of-an-inch being drilled into the patient's
skull, held in place by a vice, and a specially designed syringe or 'delivery
device' dispersing the liquid containing neural foetal stem cells into the stroke-damaged
part of the brain. Whoever successfully develops mass stem cell therapies that
can cure killers such as stroke, heart disease, diabetes or Parkinson's will have
found the holy grail of medicine and turned science fiction into fact. The trial
has been performed in rats already. The cells are injected into the damaged area
of the brain where they regenerate and multiply - leading to new connections in
the brain. "Will we see people jumping out of wheelchairs? That would be great
but at the upper end of my expectations. I'd be happy to see people being able
to walk, talk and wash themselves better after suffering a major stroke," The
Daily Mail quoted Michael Hunt, ReNeuron chief executive as saying. But of course,
like with everything else, there may be a downside to this kind of treatment too.
"Some risks we do know: the risk of operating under anaesthetic, the risk of dealing
with a stroke patient who could suffer another stroke, the risk of heart problems
during surgery, the risk of tumours, the risk of an allergic reaction," said Dr.
Keith Muir, a world-renowned neurologist. The major unknown risk is of cancerous
tumours developing, because stem cell therapy involves the fast multiplication
of cells for renewal of tissue. So far, this new therapy has been used only on
rats that had suffered from a stroke. "It's exciting and we're privileged to be
in this position. Does it keep me awake at night - the fear of the unknown? Up
to a point, yes. The pressure is immense," he added. But for some, the scientific
breakthrough is unethical. Anthony Ozimic, communications manager at the Society
for the Protection of the Unborn Child, said, "Foetal and embryonic stem cell
research is unethical, unnatural." "In no way should the bodies of the dead be
exploited in this way - particularly from an abortion," he added. He also claimed
the side-effects of using samples from embryos or foetuses can have 'horrific
results', citing one trial in the US which grafted fresh foetal tissue (rather
than cultivated stem cells) on to the brain of Parkinson's patients - leading
to hair and teeth abnormalities. There is also a vast black market, advertising
stem cell 'cures' that have not undergone proper government-regulated clinical
trials. Some people pay tens of thousands of pounds to be guinea pigs for these
'cures'. |
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