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New live oral cholera vaccine developed by Indian scientists | Scientists from three Indian institutes have developed a new live oral cholera vaccine from non-virulent innocuous strain, which was modified to formulate the vaccine. National Institute of Cholera and
Enteric Diseases (NICED) developed this new vaccine with the help of scientists
from Institute of Microbial Technology in northern Chandigarh and Institute of
Chemical Biology in Kolkata. Scientists developed this vaccine after scanning
more than 10000 isolates. "We choose a route to sort out with a virulent strain
and try to develop a vaccine out of that, and that virulent strain was discovered
at this institute, National Institute of Cholera by Dr Nair and Dr Rammurti by
scanning more than 10000 isolates," said Amit Ghosh, Emeritus Scientist, National
Institute Of Cholera and Enteric Diseases. The development of this new vaccine
was regarded as the path-breaking achievement in the history of Indian Cholera
vaccination. This new vaccine got the US patent named VA 1.4 in just ten months.
"The novelty of this strain was acknowledged when we were able to get a US patent
on it within 10 months of filing it. This is the only patent outside USA and nobody
else has done this outside USA and we did it," added Ghosh. Cholera affects thousands
of people in India each year. Nearly all the sick are poor, tribal people -- among
the most neglected groups in India -- who caught the disease from eating bad meat
or drinking polluted water. Scientists said that the new vaccine would lessen
the burden of Cholera in India , which is one of the major hotspots of Cholera
in the world. "In the past month only we have investigated six outbreaks outside
the country. So what people don't see to understand that there is a lot of Cholera
and there is a need for a public tool to lessen the burden of cholera in the country,"
said G B Nair, Director, National Institute Of Cholera and Enteric Diseases. Cholera
can cause its victims to expel massive amounts of water from their bodies through
diarrhoea and vomiting, and can kill within days if the patient fails to take
in plenty of fluids. It does respond to antibiotics. Major hotspots for cholera
and other diarrhoeal diseases include Bangladesh , China , India , Indonesia ,
Pakistan , the Philippines , and much of Africa. |
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